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AARF Act would allow pharmaceutical companies to pursue non-animal testing methods

AARF Act would allow pharmaceutical companies to pursue non-animal testing methods

Name: Alternatives to Animals for Regulatory Fairness (AARF) Act

Bill Number: HR 8736

Beagle PuppyWe know that animal test methods are inhumane, inefficient and inaccurate. For example, more than 90% of drugs that pass preclinical safety tests in dogs go on to fail in human clinical trials.

Despite this astonishing failure rate, the Food and Drug Administration (FDA) typically will not allow pharmaceutical companies to pursue alternatives that do not require animal testing—the companies are actually required by law to use animals!

The Alternatives to Animals for Regulatory Fairness (AARF) Act, recently introduced in the U.S. House of Representatives, would require the FDA to permit pharmaceutical companies to use a non-animal test as an alternative to outdated and cruel drug-safety tests on dogs and other animals.

Calls to Action:

  1. Please contact your U.S. Representative and urge them to support this bill.
  2. Spread the word! Share this page with your social network.

 

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  • Your Representative

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Message

Please support H.R. 8736 to permit pharmaceutical companies to avoid running tests on dogs

Dear [Decision Maker],

I am writing to ask you to support the newly introduced Alternatives to Animals for Regulatory Fairness (AARF) Act, H.R. 8736. This is an important piece of legislation that would require the Food and Drug Administration (FDA) to permit pharmaceutical companies to avoid running test on dogs. Specifically, this bill would allow the sponsor of a drug to use a non-animal test as an alternative to an animal test for the purposes of demonstrating the safety and effectiveness of a drug.

These tests are typically performed on dogs. Not only are the tests cruel, they're ineffective. Research conducted by the National Institutes of Health (NIH) shows that approximately 30% of medications fail in human clinical trials because they are found to be toxic, despite promising preclinical studies in animal models. An additional 60% fail due to lack of efficacy. In all, upwards of 90% of drugs that "pass" these dog tests later fail in humans.

Studies such as this also point out how the use of alternative methods to animal testing is often more effective and efficient than traditional animal use.

Testing human drugs on dogs and other animals is inhumane, inefficient and inaccurate. Passage of the AARF Act is crucial to furthering the goal of replacing, reducing and/or refining animal testing--making this a safer country for both animals and humans alike.

Thank you for your consideration.

Sincerely,
[Your Name]
[Your Address]
[City, State ZIP]